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White struggled.

Zhou Yuan held its head, and then carefully unwrapped the gauze.

The claws under the gauze scratched restlessly, and the sutures were visible to the naked eye, but it already had the initial characteristics of survival.

Zhou Yuan checked it carefully again.

The distal veins were unobstructed, the capillary circulation was normal, and the nerve reflexes were a little slow, but there was no problem at all.

Zhou Yuan moved to check Dabai and Xiaobai.

Although the therapeutic effects were inconsistent, the final results were the same. The transplanted claws... survived perfectly!

In other words, this operation is completely feasible!

Zhou Yuan stood up with some excitement.

Now... there is only one patient left to prove this theory!

If successful, then this operation is likely to be recorded in the history of the field of limb replantation in the medical community...

For the sake of accuracy, Zhou Yuan swapped the positions of the other two front and rear paws of the three mice overnight, and then gave the mice seven or eight potato chips.

Little White Mouse: I am in a difficult situation.

After three operations in one night, Zhou Yuan was a little tired. Looking at the three little white mice lying on the table, Zhou Yuan showed a satisfied smile.

The three operations went smoothly. If nothing goes wrong, the transplanted limbs of the little white mice should be able to survive.

Of course, we still have to wait until the evening to see the preliminary results.

Zhou Yuan quickly washed up and glanced at the date.

Yes, it was Monday, and today was indeed his day to go to work.

After walking for about ten minutes, Zhou Yuan arrived at the emergency department.

Liu Kai and Haiyang also happened to be at work. When they saw Zhou Yuan, they greeted him enthusiastically.

"Junior Brother Zhou Yuan? I looked at the duty roster yesterday. Wasn't Director Liu on duty this morning? How come you were the one seeing patients when I went to take over?" Liu Kai was a little confused. He said that something was wrong and he thought he had remembered the duty roster wrongly.

Zhou Yuan twitched his lips and said,"I'll take Director Liu's shift."

Liu Kai frowned and said,"Director Liu has just sent him to the operating room. It seems that they are going to take bone marrow. I don't know who it is for.""

"Stop talking, the master is here!" Haiyang glanced behind him in panic and was about to run back to his own clinic.

Zhou Yuan also looked over and saw He Jianyi rushing out of the office and rushing to the operating room.

"Haiyang, why are you running? I'm not catching you slacking off." He Jianyi looked helplessly.

Zhou Yuan instinctively became alert and followed He Jianyi to the operating room.

""Teacher, what happened?" Zhou Yuan asked.

He Jianyi's face was serious,"The bone marrow cannot be extracted!"

"Director Liu?"

"Yes, now her daughter Haoyue is lying in the transplant chamber waiting for the marrow. If the bone marrow cannot be extracted from Liu Huimin, Haoyue will die."

Zhou Yuan's face became serious.

Before the hematopoietic stem cell transplantation, the patient will generally undergo long-term chemotherapy, which will cause irreversible damage to the body. If the hematopoietic stem cells in Liu Huimin's body cannot be obtained, then Haoyue will only have one choice.

Infuse the previously damaged hematopoietic stem cells back into the body and barely survive.

Because, in addition to Liu Huimin's bone marrow matching, it is too difficult to find a second suitable bone marrow...

For bone marrow transplantation, the donor and the patient must have an HLA original match. The probability of HLA full match among siblings is one in four, while the probability of HLA match among unrelated donors in the Celestial Empire is only tens of thousands to a few hundred thousandths.

Moreover, there is another point worth mentioning.

The HLA gene is located on human chromosome 6. Like other chromosomes, chromosome 6 also comes in a pair, one from the father and one from the mother.

Therefore, half of the HLA genes of each of us are the same as those of our parents. In other words, our parents are 50% identical to us in the HLA gene.

This is an incompletely matched bone marrow, which is generally not used because it will lead to an increased incidence of postoperative complications, rejection reactions, etc.

Since Haoyue has come to the point of seeking help from Liu Huimin, it means that her condition can no longer wait, and choosing to transplant Liu Huimin's bone marrow is already a last resort.

It can also be understood that if this bone marrow transplant fails, Haoyue's life will be declared over.

"Why are you here? Can you do a bone marrow transplant?" He Jianyi tilted his head and asked.

Zhou Yuan said,"I have learned a little bit."

He Jianyi:"……"

"Hurry up and follow me!"

Zhou Yuan asked:"Which method did Director Liu use to extract hematopoietic stem cells?"

"Peripheral blood stem cell transplantation!"

"Not a classic bone marrow transplant?"Zhou Yuan frowned.

In fact, there are three methods to extract hematopoietic stem cells to treat leukemia. The first is a simple and crude bone marrow transplantation, the second is the peripheral blood stem cell transplantation that Liu Huimin is currently doing, and the third is the umbilical cord blood stem cell transplantation.

Peripheral blood stem cell transplantation uses a mobilizing agent to release hematopoietic stem cells from the bone marrow into the peripheral blood, and then uses a blood cell separator to collect hematopoietic stem cells from the circulating blood.

Compared with bone marrow transplantation, this type of transplantation has the advantages of convenient collection, no need for anesthesia for the donor, and rapid hematopoietic recovery after transplantation.

Moreover, the incidence and severity of graft-versus-host reaction after surgery will be reduced.

However, peripheral blood stem cell transplantation is a technology that has only been developed recently and is not fully mature, so there may be many defects and undiscovered dangers. What

Liu Huimin encountered today was one of them.

The two quickly made preoperative preparations, washed their hands and disinfected them in seven steps, and then entered the operating room and put on surgical gowns.

Originally, peripheral blood stem cell transplantation did not require going to the operating room. It could be done on the bed, just like drawing blood. However, because Liu Huimin's hematopoietic stem cells were not extracted,���The operating room

"It hasn't been extracted yet?"

He Jianyi took Zhou Yuan to the operating table.

"Not yet! Only a small amount of hematopoietic stem cells! We have almost drawn all the peripheral blood!" The hematologist said anxiously.

He was holding a special blood cell separator, one side was for drawing blood, and the other side was a return device.

Because only hematopoietic stem cells are needed, this instrument will retain the absorbed hematopoietic stem cells, and the blood cells and so on will be sent back to the donor's body through the return device to minimize the harm to the donor.

"Didn't the mobilization agent give enough? Why didn't the hematopoietic stem cells enter the peripheral blood?"He Jianyi asked seriously.

"We gave her enough. We gave her mobilization agents every day for a week before the bone marrow transplant, but who would have thought that the stem cells in the bone marrow were not discharged!"

Liu Huimin, lying on the bed, looked pale.

Although the large amount of blood extraction and reflux did not reduce her total blood volume, the damage to her body still existed.

"No more pumping, let's do a bone marrow transplant... I want to save my daughter." Liu Huimin's voice rang out.

"Bone marrow transplantation...cannot be performed……"The oncologist said in despair

"Why?"Liu Huimin's face turned even paler.

She was a doctor in the emergency department and had only a general understanding of this aspect. However, she also knew that if peripheral blood stem cell transplantation didn't work, bone marrow transplantation could be used!

Why didn't it work now..._

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